1520Outcomes after Implementation of a Public Health Program for HIV Partner Notification in Edmonton, Canada
Bibliographic record
Abstract
Background. We evaluated the characteristics of newly reported HIV cases and their partners after implementation of HIV Partner Notification guidelines in Edmonton, Canada in April 2010. Methods. All individuals newly diagnosed with HIV in Edmonton, Canada were interviewed by a Partner Notification Nurse (PNN) for sexual, needle sharing and perinatal contacts. Data collected on partners included whether they were located, tested, and test results. A descriptive analysis was performed on data collected from April 2010 to December 2013. Results. There were 346 newly diagnosed HIV cases during this time period: 69.4%(n = 240) were male with a median age of 37 years (IQR 29-46). The majority of male cases were Caucasian (n = 134; 55.8%) with the primary mode of transmission being sex with men (MSM) (n = 142; 59.2%). The majority of female cases were Black (n = 48; 45.3%) and reported heterosexual transmission (n = 80; 75.5%). Seventy per cent (n = 243) of HIV cases provided contact information. Cases reporting contacts were younger (35 years, IQR 28-44 vs 41 years, IQR 33-51, p < 0.001). Those who did not have sexual or IDU as the primary mode of transmission (e.g., vertical transmission) were less likely to report contacts (27.3% vs 71.6%, p = 0.004). Information on 584 contacts was provided; the median number of contacts per case was 1 (IQR 1-3). The majority (92.6%; n = 541) of contacts were exposed through sex, 5.5% (n = 32) through needle sharing and 2.2% (n = 13) perinatally. 15.6% (n = 91) were previously HIV positive. Sixty nine per cent (n = 404) were eligible by place of residence for follow up by local PNNs; 85.7% (n = 347) of these contacts were located and of these, 88.2% (n = 306) were tested resulting in 20 new cases of HIV. All new cases received HIV care; at baseline, 70% (n = 14) had normal CD4 counts (>350 x109/L), 5 cases had CD4 counts 200-350 x109/L and 1 case was below 200 x109/L. Of the previously positive contacts, 81.3% (n = 74) were sero-positive prior to their exposure to the case. 18.7% (n = 17) were sero-positive after their last exposure to the index case. Conclusion. HIV partner notification efforts, conducted by PNNs, resulted in the majority of named contacts being located and tested, including the identification of 20 previously undiagnosed cases of HIV. Disclosures. All authors: No reported disclosures.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.003 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".