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Record W2268846591 · doi:10.1139/cjz-2015-0150

Effects of long-term chronic stress on the lymphoid organs and blood leukocytes of the rat (<i>Rattus</i> <i>norvegicus</i>)

2015· article· en· W2268846591 on OpenAlexvenueno aff
S. Divyashree, Halugudde Nagaraja Sarjan, H. N. Yajurvedi

Bibliographic record

VenueCanadian Journal of Zoology · 2015
Typearticle
Languageen
FieldNeuroscience
TopicStress Responses and Cortisol
Canadian institutionsnot available
FundersUniversity of MysoreMinistry of Education, India
KeywordsBiologySpleenChronic stressLymphatic systemLymph nodeImmunologyPhysiologyLymphInternal medicineEndocrinologyPathologyMedicine

Abstract

fetched live from OpenAlex

Exposure of adult female rats (Rattus norvegicus (Berkenhout,1769)) to restraint (1 h) and after a gap of 4 h to forced swimming exercise for 15 min daily for 12 weeks resulted in a significant decrease in (i) weight of the body and lymphoid organs (spleen, thymus, and axillary lymph node), (ii) counts of total leukocytes and their subpopulation (lymphocytes, neutrophils, monocytes, eosinophils, and basophils), and (iii) healthy cells of all lymphoid organs and a significant increase in the count of apoptotic cells in all the lymphoid organs. One month after cessation of exposure to stressors (recovery group), all the parameters did not significantly differ from stress-group rats. The results may indicate that either deleterious effects of long-term chronic exposure to stress are not reversible or the 4-week recovery period is not sufficient to restore normalcy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.220
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2015
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Zoology→Same topicStress Responses and Cortisol→French-language works237,207→