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Intact peripheral chemoreflex regulation of sympathetic vasomotor tone in breath hold divers after detraining period

2009· article· en· W2282675825 on OpenAlexaff
Toni Brešković, Zoran Valić, Axel Lipp, Karsten Heusser, Vladimir Ivančev, Jens Tank, Gordan Džamonja, Jens Jordan, J. Kevin Shoemaker, Željko Dujić

Bibliographic record

VenueThe FASEB Journal · 2009
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and Diving-Related Complications
Canadian institutionsWestern University
FundersMinistry of Science and Technology, Croatia
KeywordsMedicineHypoxia (environmental)Heart rateBlood pressureAnesthesiaHemodynamicsChemoreceptorPeripheral chemoreceptorsApneaVasomotorPeripheralCardiologyInternal medicineChemistry

Abstract

fetched live from OpenAlex

We tested the hypothesis that peripheral chemoreceptor function in response to hypoxia is normal in breath‐hold divers (BHD) after detraining period. We compared ventilatory, sympathetic (MSNA), heart rate and blood pressure responses to isocapnic hypoxia in 11 BHD and 11 control subjects. The study was carried out at least one month after all divers finished most intensive apnea training. After baseline period for instrumentation, subjects breathed isocapnic hypoxic mixture to reduce arterial saturation to 0.8. During hypoxia burst frequency (MSNA f ) and total activity (MSNA t , au/min) increased similarly in both groups (27% and 60% in BHD and 30% and 66% in controls), respectively. Increased MSNA f and MSNA t returned to baseline after 20 min after termination of hypoxia. Hypoxia‐induced stimulation of minute ventilation was similar in both groups. Cardiac output was increased during hypoxia and since mean blood pressure was unchanged, total peripheral resistance was similarly reduced in both groups. We conclude that elite divers at least 1 month after the end of intensive training/competition period have normal peripheral chemosensitivity without any ventilatory, hemodynamic and autonomic differences from those observed in control subjects. This study was supported by the Croatian Ministry of Science, Education and Sports.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.265
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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