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Record W2285245801

Modelling cardiovascular disease prevention

2012· dissertation· en· W2285245801 on OpenAlexaboutno aff
Azadeh Alimadad

Bibliographic record

VenueSummit (Simon Fraser University) · 2012
Typedissertation
Languageen
FieldMedicine
TopicHealth Promotion and Cardiovascular Prevention
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDiseaseIntensive care medicineInternal medicine
DOInot available

Abstract

fetched live from OpenAlex

According to the World Health Organization (WHO), cardiovascular disease (CVD), which sits under the chronic disease umbrella, is the number one cause of death globally. Over time, we have witnessed different trends that have influenced the prevalence of CVD. One of the ways of decreasing CVD and its social costs and global fatalities is through influencing preventable CVD risk factors. Though many risk factors such as age and gender are not preventable, there are several effective behaviours that reduce the risk of CVD. To estimate the potential impact of various interventions on CVD, such as reducing blood pressure as a result of lowering sodium intake, or increasing awareness regarding healthy eating behaviour, we have used descriptive statistics and modelling. We estimated the impact of a gradual decrease in sodium intake on CVD mortality and morbidity in Canada (CA), United States (US), and Latin American (LA) countries. Our analysis shows that small changes in sodium intake at the population level can make an important difference in the total number of CVD events that can be prevented. Using data in Canada and France we also explored the potential role of individual decision making on daily sodium consumption. Our analysis showed that the main obstacle to consumers making healthier choices appears to be neither the availability of products, nor the price. Consumers may be more hampered by the difficulty of comparing food labels than by the availability of lower sodium products. Using Canadian data, we also examined the potential impact of having a positive family history of CVD on CVD mortality. Based on our analysis, father stroke before the age of 60 was a strong predictor for CVD mortality. Following this analysis, we used mathematical models, to improve our understanding of the impact on CVD of changes in the trend of CVD risk factors such as obesity, social and environmental influences. We investigated each of these risk factors separately, in order to have a clear foundation for more complex models. We also used a Fuzzy Cognitive Map (FCM) that considered a wide range of interactions and interrelationships between different CVD risk factors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.939
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.263
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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