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Record W2290883706

Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006

2009· dissertation· en· W2290883706 on OpenAlexaboutno aff
S. K. Glass

Bibliographic record

VenueThe Atrium (University of Guelph) · 2009
Typedissertation
Languageen
FieldMedicine
TopicAntibiotics Pharmacokinetics and Efficacy
Canadian institutionsnot available
Fundersnot available
KeywordsAntimicrobialEnvironmental healthMedicineBiologyMicrobiology
DOInot available

Abstract

fetched live from OpenAlex

Multivariable linear and negative binomial models were produced to assess relationships among socioeconomic and influenza rate data with the use of macrolide and fluoroquinolone antimicrobials by Canadians. Varying results were found both among and between the macrolide and fluoroquinolone groups; however, a pattern of accessibility to care was apparent. Cheaper antimicrobials were used most often in the most disadvantaged populations, and more expensive antimicrobials were used most frequently in advantaged populations. Significant interactions were found between influenza and socioeconomic variables relating to unemployment, education, and degree of poverty in a population. Results suggest that antimicrobials are being prescribed and consumed at inappropriate rates in both disadvantaged and affluent populations in Canada. In order to reduce antimicrobial use and the further development of antimicrobial resistance in Canada, we suggest that responsible antimicrobial stewardship be practiced and promoted by all physicians in community and hospital settings, particularly during the influenza season.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.089

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.268
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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