Formalizing clinical practice guideline for clinical decision support systems
Bibliographic record
Abstract
Clinical practice guidelines are valuable sources of clinical knowledge for healthcare professionals. However, the passive dissemination of clinical practice guidelines like publishing in medical journals is ineffective in changing clinical practice behaviour. In this work, we proposed a framework to help adopting an active clinical practice guideline dissemination approach by automatically extracting clinical knowledge from clinical practice guidelines into a clinical decision support system-friendly format. The proposed framework is intended to help human modellers by automating some of the manual formalization activities in order to minimize their manual effort. We evaluated our framework using all recommendations from two clinical practice guidelines produced by the Scottish Intercollegiate Guidelines Network: the 'Management of lung cancer' clinical practice guideline and the 'Management of chronic pain' clinical practice guideline. We conclude that the proposed framework can be effectively used to formalize drug and procedure recommendation in clinical contexts.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.043 | 0.101 |
| Meta-epidemiology (narrow) | 0.002 | 0.002 |
| Meta-epidemiology (broad) | 0.001 | 0.004 |
| Bibliometrics | 0.006 | 0.003 |
| Science and technology studies | 0.002 | 0.003 |
| Scholarly communication | 0.010 | 0.007 |
| Open science | 0.006 | 0.007 |
| Research integrity | 0.004 | 0.006 |
| Insufficient payload (model declined to judge) | 0.007 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".