Increased focal and diffuse cerebral demand after concussion
Bibliographic record
Abstract
Aim: To examine cortical activation during a memory task in children with and without post-concussion symptoms (PCS) following concussion. Methods: A case-controlled study within the PlayGame Trial ( www.playgametrial.ca ). Children (aged 8-18 years) with PCS at 1-month post-injury were eligible. The fMRI task was a working memory task. Pre-processing and single-subject analysis were performed in FSL. Group activation and inter-group difference maps were extracted. Results: 11 symptomatic, 12 asymptomatic, and 11 controls without concussion participated. Groups were similar in age (14.9, 14.0, and 13.8yrs; p=0.46), sex (p=0.984) and time post-injury (symptomatic: 37d; asymptomatic 35d; p=0.573). Compared with controls, symptomatic children demonstrated greater activation especially in the bilateral orbito-frontal cortex and cerebellum. A similar, less pronounced pattern was observed in asymptomatic subjects. Conclusions: Similar to adult studies, increased network activation may represent decreased “efficiency” and explain the cognitive fatigue in PCS. Further, children who are “asymptomatic” may not yet be fully recovered.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".