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Record W2299716255 · doi:10.1016/s0168-8278(15)30136-7

O117 : Predictors of clinical response: Results from a large, randomized controlled study with tenofovir disoproxil fumarate (TDF) plus peginterferon alfa-2A (PEG) combination for chronic hepatitis B (CHB)

2015· article· en· W2299716255 on OpenAlexaff
Henry Lik‐Yuen Chan, Sang Hoon Ahn, Wan‐Long Chuang, Aric J. Hui, Fehmı Tabak, Rajiv Mehta, J. Petersen, C.-M. Lee, Xiao Ma, Florin Alexandru Căruntu, Won Young Tak, M Elkhashab, Lanjia Lin, Phillip Dinh, Eduardo B. Martins, Prista Charuworn, John McHutchinson, G. Mani Subramanian, Seng Gee Lim, Graham R. Foster, Scott Fung, LE Morano, Didier Samuel, Kosh Agarwal, Ramazan Idılman, Simone I. Strasser, Marı́a Buti, Giovanni Battista Gaeta, George Papatheodoridis, Robert Flisiak, Patrick Marcellin

Bibliographic record

VenueJournal of Hepatology · 2015
Typearticle
Languageen
FieldMedicine
TopicHepatitis B Virus Studies
Canadian institutionsUniversity of TorontoToronto General HospitalToronto Liver Centre
Fundersnot available
KeywordsTenofovirChronic hepatitisMedicinePeginterferon alfa-2aInternal medicineRandomized controlled trialPharmacologyGastroenterologyVirologyVirusRibavirinHuman immunodeficiency virus (HIV)

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.019
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.241
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0110.019
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.360
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2015
Admission routes1
Has abstractno

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