Bibliographic record
Abstract
Depression is a heterogeneous collection of phenotypes sharing partially overlapping genes, neurobiology, and symptoms. This chapter applies an evolutionary perspective to the distinct etiologies and functions of three reliably identified depressive phenotypes: sickness behavior, starvation depression, and melancholia (i.e., depression with melancholic features). Infection and food shortage are evolutionarily ancient problems, and so sickness behavior and starvation depression probably evolved first. Melancholia probably evolved more recently and shows signs of an evolutionary design for a cognitive function. More specifically, evidence suggests that melancholia is an adaptation for promoting analytical reasoning, and probably evolved as an adaptive response to complex problems involving resource management or conflicts with close social partners. These depressive phenotypes, although distinct, are functionally similar, which explains the overlapping genetics, neurobiology, and symptomatology. In all three, depressive symptoms help the body coordinate the reallocation of limited energy resources in response to persistent threats.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".