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Record W2308374568 · doi:10.1136/ebmed-2016-110391

Influenza vaccination and egg allergy: another step forward

2016· letter· en· W2308374568 on OpenAlexaff
Anne Des Roches, Louis Paradis

Bibliographic record

VenueEvidence-Based Medicine · 2016
Typeletter
Languageen
FieldMedicine
TopicFood Allergy and Anaphylaxis Research
Canadian institutionsCentre Hospitalier Universitaire Sainte-Justine
FundersMedical Research Council
KeywordsEgg allergyMedicineVaccinationLive attenuated influenza vaccineContraindicationAllergyInfluenza vaccineImmunologyPediatricsFood allergyAlternative medicine

Abstract

fetched live from OpenAlex

Commentary on: Turner PJ, Southern J, Andrews NJ, et al. Safety of live attenuated influenza vaccine in young people with egg allergy: multicentre prospective cohort study. BJOG 2015;351:h6291. The occurrence of epidemics, like H1N1 in 2009, mobilises the scientific community to focus on resolution of problems. For many years, flu vaccination was a dilemma for physicians taking care of patients with an egg allergy. The small amount of egg found in the vaccine was considered a contraindication to immunisation. However, most people with this allergy are young and asthmatic, thus clearly the ones who could greatly benefit from this immunisation. While fractioned administration of intramuscular trivalent inactivated influenza vaccine (TIV) was previously deemed safe in egg allergic patients,1 a first publication in 2010 demonstrated the absence of anaphylactic reaction after H1N1 immunisation …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Other
About the Canadian research system: no · About a Canadian topic: no
Not applicablelow
gptno category
Domain: not available · Genre: Commentary
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.071
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.344
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designNot applicable · Other design
Domainnot available
GenreOther · Commentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2016
Admission routes1
Has abstractyes

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