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Record W2313819752 · doi:10.1021/jp4009042

CNT Induced β-Phase in Polylactide: Unique Crystallization, Biodegradation, and Biocompatibility

2013· article· en· W2313819752 on OpenAlexaff
Narendra K. Singh, Sunil Kumar Singh, Debabrata Dash, Prasad Gonugunta, Manjusri Misra, Pralay Maiti

Bibliographic record

VenueThe Journal of Physical Chemistry C · 2013
Typearticle
Languageen
FieldMaterials Science
Topicbiodegradable polymer synthesis and properties
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsBiocompatibilityMaterials scienceCrystallizationCarbon nanotubeChemical engineeringSurface modificationFourier transform infrared spectroscopyBiodegradationPolymerDifferential scanning calorimetryNanocompositeComposite materialOrganic chemistryChemistry

Abstract

fetched live from OpenAlex

The effect of multi-walled carbon nanotube (MWCNT) on the crystal structure, unique crystallization, mechanical behavior, enzymatic degradation, and significant improvement in biocompatibility of polylactide (PLA) nanohybrid has been reported. Functionalization of carbon nanotube using stearyl alcohol has been carried out and has been confirmed through FTIR and Raman spectroscopy. PLA nanohybrids have been synthesized using functionalized and neat MWCNT through solution route, and the improved level of dispersion of MWCNT has been achieved in PLA matrix. High-magnification transmission electron microscope images indicate the unique adsorption of PLA chain leading to the crystallization of β-phase structure on the surface of the functionalized MWCNT against the usual crystallized α-form of pure PLA. The presence of β phase in nanohybrids has been confirmed through electron diffraction pattern, differential scanning calorimetry thermograms, and X-ray diffraction patterns. The improved and diverse mechanical, thermal properties, and crystallization kinetics have been explored with the special emphasis on the relaxation behavior of β phase in dynamic mechanical analysis. The cause of these developments has been appraised from the interaction point of view as calculated from the interaction parameter (χ) using melting-point depression technique. The rate of biodegradation has been studied in detail with plausible mechanism in Proteinase K enzyme media showing their specificity and tuning of biodegradation rate followed by their optimization. For biomedical applications, the effect of pure polymer and nanohybrids on circulating blood cells has been evaluated in detail, and the hemocompatible nature of the nanohybrids has been revealed, suppressing the cellular toxicity of MWCNT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.241

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.257
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations65
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueThe Journal of Physical Chemistry CSame topicbiodegradable polymer synthesis and propertiesFrench-language works237,207