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Record W2314775748 · doi:10.1115/fedsm-icnmm2010-30306

Experimental Investigation of Dielectrophoretic Behavior of Myoglobin and Silica Particles on a Microelectrode Chip

2010· article· en· W2314775748 on OpenAlexafffund
Naga Siva Kumar Gunda, Sushanta K. Mitra

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldEngineering
TopicMicrofluidic and Bio-sensing Technologies
Canadian institutionsUniversity of Alberta
FundersCMC Microsystems
KeywordsDielectrophoresisMyoglobinMicroelectrodeMaterials scienceElectrokinetic phenomenaNanotechnologyBiomoleculeMicrofabricationElectrodeMicrofluidicsChemistryFabrication

Abstract

fetched live from OpenAlex

Dielectrophoresis (DEP) is one of the nondestructive electrokinetic techniques that has immense capability for manipulating nano-sized biomolecules like myoglobin. The present study investigates the behavior of myoglobin molecules on a microelectrode surface under the influence of dielectrophoresis. Microelectrodes are fabricated in transparent borofloat glass wafers with a sequence of microfabrication steps like piranha cleaning, metal deposition, optical lithography and etching. A detailed description of experimental setup to conduct DEP experiments on myoglobin is presented with a brief overview of myoglobin preparation. Silica particles are used to mimic the myoglobin molecules. Both positive DEP and negative DEP effects on silica particles is observed and positive DEP effect on myoglobin is also observed. Positive DEP on silica particles is observed at applied voltage range of 5–10V and frequency range of DC to 1KHz. Negative DEP effect on silica particles is observed at 10V applied voltage and 10KHz to 40KHz frequency range. The positive DEP effect of myoglobin is observed at applied voltage of 5V and frequency of 5kHz.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.200
Teacher spread0.193 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes2
Has abstractyes

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