Calcinosis and Rapidly Destructive Arthropathy Associated with Anti-Jo1 Antibody
Bibliographic record
Abstract
We report here a rare case of marked calcinosis and rapidly destructive arthropathy associated with anti-Jo1 antibody.A 74-year-old white woman presented to the rheumatology clinic in 2008 with a 5-year history of polyarthralgia affecting her left hip, right elbow, left shoulder, and hands.Hand and elbow radiographs (Figure 1) showed destructive arthropathy thought to be attributable to severe erosive osteoarthritis or crystal arthritis.Repeat radiographs in 2010 showed extensive periarticular calcinosis and complete destruction of the right elbow joint.Similar changes were noted on the repeat hand radiograph in 2012 (Figure 2).Immunological profile revealed strongly positive antinuclear antibody in a nucleolar pattern and anti-Jo1 antibody.Muscle biopsy showed numerous atrophic fibers, but no active inflam-
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".