Neural Toxicology and Pathology of Domoic Acid
Bibliographic record
Abstract
Domoic acid is a potent neurotoxin when intake via contaminated seafood in bulk quantity, results in neural tissue necrosis. It caused an outbreak of human poisoning in Canada in 1987 by the consumption of contaminated blue mussels ( Mytilus edulis ), produced by red alga Chondria armataand and the genus Pseudo nitzschia . Domoic acid targets the glutamate receptors and the poisoning was characterized by memory impairment and brain disorders which led to the name Amnesic Shellfish Poisoning (ASP). Domoic acid has intoxicated wild animals and contaminated coastal waters since the 1987 incident. Hence it poses a global health and safety threat to significant human and wild animal lives populated at the shorelines. The present review aims to extend the understandings of ASP, DA induced toxicology and pathology which are critical for human health and wildlife safety. Keywords: Domoic Acid, Amnesic Shellfish Poisoning, Neurotoxicology, Neuropathology.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".