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Enteral Nutrition in Crohn's Disease in Childhood

2001· article· en· W2318160669 on OpenAlexaff
Anne M. Griffiths

Bibliographic record

VenueJournal of Pediatric Gastroenterology and Nutrition · 2001
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsMedicineParenteral nutritionCrohn's diseaseDiseaseInflammatory bowel diseaseNatural historyEnteral administrationIntensive care medicineAdverse effectIntervention (counseling)Crohn diseaseMedical nutrition therapyPediatricsInternal medicinePsychiatry

Abstract

fetched live from OpenAlex

To the Editor: I am very pleased that Professor Walker-Smith has written to further elaborate on the United Kingdom's experience with enteral nutrition in active Crohn's disease. As discussed in my editorial, the difference between United Kingdom and North American management of children with newly diagnosed Crohn's disease is striking. All of us who treat inflammatory bowel disease (IBD), and, indeed, also our patients and their parents should consider enteral nutrition as an option for primary therapy. The attitude of physicians inevitably influences patients in their acceptance or rejection of any treatment or intervention. I agree that prospectively accrued data comparing the frequency of mucosal healing with enteral nutrition versus corticosteroids are important. So, too, is information related to the long-term natural history of Crohn's disease treated from the outset with enteral nutrition versus corticosteroids. If either of these comparisons demonstrates superiority of enteral nutrition, North American recommendations concerning optimal treatment would have to be altered. In the meantime, we should at least endorse enteral nutrition as a treatment without cosmetic adverse effects that “works” frequently in patients with newly diagnosed disease. Given that there is no evidence that amino-acid–based formulae are required, we should encourage the use of more palatable formulae to facilitate oral consumption. Anne M. Griffiths

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.007
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.013
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0070.012
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.213
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2001
Admission routes1
Has abstractyes

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