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Record W2318294594 · doi:10.5114/bta.2015.56570

Artificial life forms: the strains of the future?

2016· article· en· W2318294594 on OpenAlexaff
Kalyani Rajalingham

Bibliographic record

VenueBioTechnologia · 2016
Typearticle
Languageen
FieldEngineering
TopicBiomedical and Engineering Education
Canadian institutionsMcGill University
Fundersnot available
KeywordsBiology

Abstract

fetched live from OpenAlex

Synthetic biology is the field of biology that is involved in the manufacturing of genomic material designed by man with subsequent introduction into a chassis. A synthetic life has a minimal genome of about 500-800 genes as well as a few additional genes required to fulfill a particular task. Synthetic life forms can be used for the production of valuable target compounds such as the antimalarial drug artemisinin. This technology is applicable to all subfields of biotechnology and biology, but it is, in particular, relevant for the making of target compounds; it can be used for the making of biofuels, drugs, energy, artificial photosynthesis, in medicine, bioremediation/biosensors, in the chemical industry, and in agriculture. It is believed that these novel artificial strains will become the ruling strains in the near future with many a use in many a field. This paper outlines the positive aspects of synthetic life forms as well as the methods used to generate artificial life forms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0010.004
Scholarly communication0.0030.007
Open science0.0010.001
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.183
Teacher spread0.176 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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