CMCF 08ID-1 beamline at the Canadian Light Source
Bibliographic record
Abstract
The Canadian Macromolecular Crystallography Facility has more than sixty participating protein crystallographers, located across Canada, will eventually consist of three beamlines; two insertion devices beamlines and one bending magnet beamline [1]. The first insertion device beamline (08ID-1) was intended to be a highly efficient and flexible, capable of satisfying the requirements of the most challenging and diverse crystallographic experiments, i.e. physically small crystals with large unit cell dimensions. The recently funded bending magnet 08B1 beamline has been designed to be dedicated to highthroughput data collection capable of being accessed remotely. The third, an undulator based 08ID-2 beamline, is envisioned to have micro-focusing capabilities with some restrictions in energy range. The CMCF 08ID-1 beamline has been built and is now being commissioned. The beamline is illuminated by a small-gap in-vacuum hybrid undulator (SGU), located in the upstream half of the straight section, and chicaned inboard by 0.75 mrad. The downstream half of this section is reserved for the 08ID-2 beamline SGU. The overall design of the beamline contains white beam slits (WBS), a double crystal monochromator (DCM) equipped with an indirectly cryocooled first crystal and a sagittally-focusing second crystal followed by a vertically focussing mirror (VFM). The beamline is completed with an innovative and very robust endstation, including the MarMosaic225 CCD X-ray detector. Most of the beamline components were manufactured by ACCEL Instruments GmbH (Germany). The beamline controls, similarly for the CLS facility, are being developed based on the EPICS platform. The beamline is equipped with a Rontek Spectrometer System (XFLASH 101A) for carrying out X-ray absorption near edge structure spectroscopy (XANES) for multiwavelength anomalous diffraction (MAD) experiments, and X-ray fluorescence (XRF) for the detection of metal atoms in protein derivative crystals. The beamline will be equipped with a robotic cryogenic sample changer that is based on the SSRL design (SAM). At the meeting we will present recent results of experiments performed at the CMCF 08ID-1 beamline. The CLS is supported by NSERC, NRC, CIHR and the University of Saskatchewan..
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.003 | 0.004 |
| Science and technology studies | 0.007 | 0.001 |
| Scholarly communication | 0.003 | 0.002 |
| Open science | 0.003 | 0.002 |
| Research integrity | 0.001 | 0.004 |
| Insufficient payload (model declined to judge) | 0.088 | 0.032 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".