MétaCan
Menu
Back to cohort
Record W2321144071 · doi:10.1142/9781848162648_0006

MSDASH: MASS SPECTROMETRY DATABASE AND SEARCH

2008· article· en· W2321144071 on OpenAlexaff
Zhan Wu, Gilles Lajoie, Bin Ma

Bibliographic record

VenueComputational Systems Bioinformatics · 2008
Typearticle
Languageen
FieldChemistry
TopicMass Spectrometry Techniques and Applications
Canadian institutionsWestern University
Fundersnot available
KeywordsComputer scienceMass spectrometryIon-mobility spectrometry–mass spectrometryDatabaseInformation retrievalChemistrySelected reaction monitoringChromatographyTandem mass spectrometry

Abstract

fetched live from OpenAlex

Along with the wide application of mass spectrometry in proteomics, more and more mass spectrometry data are becoming publicly available. Several public mass spectrometry data repositories have been built on the Internet. However, most of these repositories are devoid of effective searching methods. In this paper we describe a new mass spectrometry data library, and a novel method to efficiently index and search in the library for spectra that are similar to a query spectrum. A public online server have been set up and demonstrated outstanding speed and scalability of our methods. Together with the mass spectrometry library, our searching method can improve the protein identification confidence by comparing a spectrum with the ones that are already characterized in the database. The searching method can also be used alone to cluster the similar spectra in a mass spectrometry dataset together, in order to to improve the speed and accuracy of the protein identification or quantification.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Software · Consensus signal: Software
Teacher disagreement score0.031
Threshold uncertainty score0.105

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.009
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0090.010
Science and technology studies0.0010.001
Scholarly communication0.0030.004
Open science0.0060.005
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0310.045

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.264
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2008
Admission routes1
Has abstractyes

Explore more

Same venueComputational Systems BioinformaticsSame topicMass Spectrometry Techniques and ApplicationsFrench-language works237,207