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Testing the Effects of Speciation and Mutation Rates on Distance-Based Phylogenetic Tree Construction Accuracy Using EcoSim

2014· article· en· W2322206302 on OpenAlexaff
Ryan Scott, Robin Gras

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsUniversity of Windsor
Fundersnot available
KeywordsPhylogenetic treeGenetic algorithmMutation rateComputational phylogeneticsMutationTree (set theory)Computer scienceEvolutionary biologyBiologyMathematicsGeneticsPhylogenetic networkGeneCombinatorics

Abstract

fetched live from OpenAlex

Biologists regularly construct phylogenetic trees during their research in order to understand the evolutionary history of their subjects. Typically the actual phylogenetic tree is not known, and thus the phylogenetic tree produced is only an estimate. There are two main categories of phylogenetic tree construction, distance-based methods and character-based methods. In all cases, the effects of mutation rate and genetic compactness of species clusters on phylogenetic tree construction accuracy are not well understood. In order to test the correctness of a particular method, it is imperative to perform the study in a system for which the actual phylogenetic tree is known. Thus, realistic and complex simulations in which evolution and speciation occur provide a perfect platform for such a study. EcoSim is such a simulation, and is a simulation

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.032
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.032
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.237
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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