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Record W2323054755 · doi:10.1111/jdv.13636

Fragility of epidermis in newborns, children and adolescents

2016· review· en· W2323054755 on OpenAlexaff
Ulrike Blume‐Peytavi, Jerry Tan, Dominique Tennstedt, F. Boralévi, Gabriella Fabbrocini, Antonio Torrelo, R. Soares‐Oliveira, Marek Haftek, Ana B. Rossi, Marie‐Dominique Thouvenin, J. Mangold, M. Galliano, Hélène Hernandez-Pigeon, Marie-Françoise Ariès, C. Rouvrais, S. Bessou‐Touya, Hélène Duplan, N. Castex‐Rizzi, V. Mengeaud, P Ferret, Elodie Clouet, M. Saint Aroman, Cristhian Carrasco, Christine Coutanceau, B. Guiraud, Sanwarjit Boyal, Anne Herman, H. Delga, Krysta Biniek, Reinhold H. Dauskardt

Bibliographic record

VenueJournal of the European Academy of Dermatology and Venereology · 2016
Typereview
Languageen
FieldHealth Professions
TopicNeonatal skin health care
Canadian institutionsWindsor Clinical ResearchUniversity of WindsorWestern University
Fundersnot available
KeywordsAtopic dermatitisMedicineDermatologyAcneDry skinRosaceaPathologicalEpidermis (zoology)PathologyAnatomy

Abstract

fetched live from OpenAlex

Within their first days of life, newborns' skin undergoes various adaptation processes needed to accommodate the transition from the wet uterine environment to the dry atmosphere. The skin of newborns and infants is considered as a physiological fragile skin, a skin with lower resistance to aggressions. Fragile skin is divided into four categories up to its origin: physiological fragile skin (age, location), pathological fragile skin (acute and chronic), circumstantial fragile skin (due to environmental extrinsic factors or intrinsic factors such as stress) and iatrogenic fragile skin. Extensive research of the past 10 years have proven evidence that at birth albeit showing a nearly perfect appearance, newborn skin is structurally and functionally immature compared to adult skin undergoing a physiological maturation process after birth at least throughout the first year of life. This article is an overview of all known data about fragility of epidermis in 'fragile populations': newborns, children and adolescents. It includes the recent pathological, pathophysiological and clinical data about fragility of epidermis in various dermatological diseases, such as atopic dermatitis, acne, rosacea, contact dermatitis, irritative dermatitis and focus on UV protection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.524
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.417
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations61
Published2016
Admission routes1
Has abstractyes

Explore more

Same venueJournal of the European Academy of Dermatology and VenereologySame topicNeonatal skin health careFrench-language works237,207