Vitamin E Contact Allergy: A Controversial Subject
Bibliographic record
Abstract
Although vitamin E has been described as a source of allergic contact dermatitis (ACD), in only a few cases a true sensitization has been confirmed. We describe 2 cases of suspected ACD to vitamin E products. Patch tests and repeated open application tests were performed with the patients' own offending products. Then, patch tests with tocopherol acetate at different concentrations and further patch tests and repeated open application tests with a new sample of the product were carried out. Whereas the first sessions of tests gave positive reactions, the last sessions of tests performed with new samples were negative. Based on these results, we conclude that both our patients probably developed a true vitamin E ACD. However, as vitamin E exerts an anti-inflammatory effect and is an unstable molecule and its allergic potential change during the time, when ACD to vitamin E is tested a bimodal behavior of this molecule may be expected.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".