OCULAR NOCARDIOSIS IN A RENAL TRANSPLANT PATIENT
Bibliographic record
Abstract
In Brief Purpose: To describe a case of an immunosuppressed patient with history of renal transplant that presented with sudden unilateral loss of vision. Methods: Case report. Review of medical records. Results: A 49-year-old man with history of renal transplantation presenting with visual symptoms without initial systemic manifestations. Because of the rarity of ocular involvement, the patient's diagnosis of Nocardia asteroides endophthalmitis was delayed culminating in systemic involvement and necessitating enucleation of the eye. Conclusion: Nocardiosis is a serious life-threatening complication in immunosuppressed patients. Visual symptoms and endophthalmitis in this population should raise the suspicion of a possible serious systemic infection like nocardia. Kidney transplantation, the preferred treatment for end-stage renal disease, can be complicated by opportunistic infections. Nocardiosis is a potentially fatal infection caused by a gram-positive organism that primarily affects immunosuppressed patients. We report a 49-year-old man with a history of renal transplantation who presented with visual symptoms without initial systemic manifestations. Because of the rarity of ocular involvement, the patient's diagnosis of Nocardia asteroides endophthalmitis was delayed. A repeat workup revealed systemic involvement. This report is meant to raise physicians' awareness about the seriousness of ocular symptoms in immunosuppressed patients and may be the sole warning sign of a life-threatening systemic disease.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".