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Record W2325804722 · doi:10.1097/icb.0b013e31822477c4

OCULAR NOCARDIOSIS IN A RENAL TRANSPLANT PATIENT

2011· article· en· W2325804722 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueRetinal Cases & Brief Reports · 2011
Typearticle
Languageen
FieldMedicine
TopicActinomycetales infections and treatment
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineNocardiosisEnucleationEndophthalmitisComplicationNocardiaRenal transplantOpportunistic infectionTransplantationPopulationKidney transplantationSurgeryIntensive care medicineImmunology

Abstract

fetched live from OpenAlex

In Brief Purpose: To describe a case of an immunosuppressed patient with history of renal transplant that presented with sudden unilateral loss of vision. Methods: Case report. Review of medical records. Results: A 49-year-old man with history of renal transplantation presenting with visual symptoms without initial systemic manifestations. Because of the rarity of ocular involvement, the patient's diagnosis of Nocardia asteroides endophthalmitis was delayed culminating in systemic involvement and necessitating enucleation of the eye. Conclusion: Nocardiosis is a serious life-threatening complication in immunosuppressed patients. Visual symptoms and endophthalmitis in this population should raise the suspicion of a possible serious systemic infection like nocardia. Kidney transplantation, the preferred treatment for end-stage renal disease, can be complicated by opportunistic infections. Nocardiosis is a potentially fatal infection caused by a gram-positive organism that primarily affects immunosuppressed patients. We report a 49-year-old man with a history of renal transplantation who presented with visual symptoms without initial systemic manifestations. Because of the rarity of ocular involvement, the patient's diagnosis of Nocardia asteroides endophthalmitis was delayed. A repeat workup revealed systemic involvement. This report is meant to raise physicians' awareness about the seriousness of ocular symptoms in immunosuppressed patients and may be the sole warning sign of a life-threatening systemic disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.226
Threshold uncertainty score0.552

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.243
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it