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Imaging of Ocular Angle Structures with Fourier Domain Optical Coherence Tomography

2013· article· en· W2326630534 on OpenAlexaff
Sanjay Asrani, Mei Young, Jing Xu, Marinko V. Šarunic

Bibliographic record

VenueJOURNAL OF CURRENT GLAUCOMA PRACTICE · 2013
Typearticle
Languageen
FieldMedicine
TopicGlaucoma and retinal disorders
Canadian institutionsSimon Fraser UniversityUniversity of British Columbia
Fundersnot available
KeywordsSchlemm's canalOptical coherence tomographyTrabecular meshworkFourier domainGlaucomaOpticsScleraOphthalmologyMedicinePhysics

Abstract

fetched live from OpenAlex

BACKGROUND: Imaging of the Schlemm's Canal is complicated by the small physiological size and the location several hundred microns beneath the sclera. Noninvasive imaging of Schlemm's canal and Trabecular Meshwork (TM) in vivo with Fourier Domain Optical Coherence Tomography (FD OCT) can provide clinicians with a powerful tool to visualize ocular angular structures crucial for glaucoma management. PURPOSE: To investigate the appearance of Schlemm's canal and TM on FD OCT images. METHODS: FD OCT images of the Schlemm's canal and TM were obtained with three different wavelengths using prototype FD OCT systems in a normal volunteer. FD OCT images using the 1310 nm wavelength prototype were obtained in three representative cases of glaucoma surgery performed on angle structures. RESULTS: The longer imaging depth and deeper tissue penetration of the 1310 nm system provided the clearest image of the TM and Schlemm's canal in the normal patient. In case 1, images pre- and post-trabectome surgery clearly showed the location and appearance of TM. In case 2, images post-canaloplasty surgery showed the location and appearance of Schlemm's canal. In case 3, images pre- and post-trabeculotomy surgery further confirms the appearance and location of the Schlemm's canal and TM. CONCLUSION: Operating wavelength of the FD OCT system and exact location of the scan across different meridians minimally affects the appearance of the ocular anatomy. The postoperative images of three angle glaucoma surgeries confirmed the location of Schlemm's canal and TM. How to cite this article: Asrani S, Young M, Xu J, Sarunic MV. Imaging of Ocular Angle Structures with Fourier Domain Optical Coherence Tomography. J Current Glau Prac 2013;7(2):85-87.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.554

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.285
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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