Thermally Responsive 2-Hydroxyethyl Methacrylate Polymers: Soluble–Insoluble and Soluble–Insoluble–Soluble Transitions
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
2-Hydroxyethyl methacrylate (HEMA)-based (co)polymers showed soluble to insoluble (S–I) thermoresponses, as measured by turbidimetry, when heated in aqueous solutions of appropriate ionic strength and/or pH. Surprisingly, many of the polymers showed a second insoluble to soluble (I–S) thermoresponse at higher temperatures, probably as a result of breaking of polymer–polymer H-bonding that allowed redissolution of the polymer chains. The thermoresponse of the charged copolymers was very sensitive to the polymer concentration, pH, and ionic strength likely due to the role of charge screening in the chain collapse and aggregation necessary to observe cloud points. Urea, a commonly used “H-bond breaker”, raised the cloud point (and decreased the clearing point for systems that showed I–S transitions); however, subsequent cooling or heating runs in the presence of urea often showed dramatically different thermoresponses as a result of urea hydrolysis, leading to a pH change and/or polymer hydrolysis at high temperature. Marked hysteresis or changes from run to run were seen for some systems because of polymer precipitation or slow rehydration of phase-separated material or, in some cases, slow hydrolysis of HEMA units.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.005 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it