MétaCan
← all works

Computational Lipidomics with insane: A Versatile Tool for Generating Custom Membranes for Molecular Simulations

2015· article· en· 1,212 citations· W2327174080 on OpenAlex· 10.1021/acs.jctc.5b00209

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
Simulation or modellingBench or experimentalTheoretical or conceptual
Classifier consensus
Simulation or modelling
Teacher imitation scores

Codex

Simulation or modelling0.984
Theoretical or conceptual0.017
Other design0.004
Bench or experimental0.002
Randomized trial0.001
Scholarly communication0.001
Not applicable0.000
Metaresearch0.000
Case report0.000
Open science0.000
Qualitative0.000
Observational0.000
Systematic review0.000
Bibliometrics0.000
Meta-analysis0.000
Meta-epidemiology (narrow)0.000
Science and technology studies0.000
Research integrity0.000
Meta-epidemiology (broad)0.000
Non-randomized trial0.000

Gemma

Simulation or modelling0.961
Bench or experimental0.038
Theoretical or conceptual0.036
Not applicable0.006
Metaresearch0.001
Non-randomized trial0.000
Qualitative0.000
Randomized trial0.000
Case report0.000
Open science0.000
Meta-epidemiology (broad)0.000
Bibliometrics0.000
Science and technology studies0.000
Scholarly communication0.000
Research integrity0.000
Meta-epidemiology (narrow)0.000
Systematic review0.000
Meta-analysis0.000
Observational0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.013
GPT teacher head0.271
Teacher spread
0.258 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

For simulations of membranes and membrane proteins, the generation of the lipid bilayer is a critical step in the setup of the system. Membranes comprising multiple components pose a particular challenge, because the relative abundances need to be controlled and the equilibration of the system may take several microseconds. Here we present a comprehensive method for building membrane containing systems, characterized by simplicity and versatility. The program uses preset, coarse-grain lipid temp…

Retrieved from PubMed through NCBI EFetch. Structured section labels are preserved.