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Record W2328012680 · doi:10.1017/s031716710001252x

Gouty Arthropathy of the Axial Skeleton Causing Cord Compression and Myelopathy

2011· article· en· W2328012680 on OpenAlexaffvenue
George M. Ibrahim, Julius O. Ebinu, Laurence A. Rubin, Lyne Noël de Tilly, Julian Spears

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2011
Typearticle
Languageen
FieldMedicine
TopicGout, Hyperuricemia, Uric Acid
Canadian institutionsSt. Michael's HospitalUniversity of Toronto
Fundersnot available
KeywordsMyelopathySkeleton (computer programming)MedicineArthropathyAnatomySpinal cordPathologyOsteoarthritis

Abstract

fetched live from OpenAlex

A 70-year-old Caucasian female with a past medical history of hypertension, chronic renal insufficiency, dyslipidemia, hypothyoidism, anemia, congestive heart failure, recent humeral fracture, and longstanding gout, presented with a one-year history of progressive weakness and falls, increasing "clumsiness" in her hands and weakness of the lower extremities.Bowel and bladder function were intact.On examination, resistance in the lower extremities was reduced, sensation was diminished bilaterally, and hyperreflexia with sustained ankle clonus noted.Computed tomogram (CT) and magnetic resonance imaging (MRI) of the spine (Figures 1 and2) revealed a bilateral destructive process involving the posterior elements of T1 and T2, centered on the facet joints.There was anterior listhesis of T1 on T2 and increased T2 signal within the spinal cord.She underwent posterior decompression with instrumented fusion.Surgical pathology of the spinal mass was sent for histology and crystal analysis (Figure 3).Monosodium urate crystals were detected.The patient's deficits gradually improved postoperatively and the management of her gout (Serum Uric Acid [SUA] at presentation 792 umol/L) was optimized.Gouty arthropathy of the axial skeleton is well-described, affecting up to 17% of patients with chronic gout and is typically localized to the sacroiliac joints and the facet joints of spinal

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.265
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2011
Admission routes2
Has abstractyes

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Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences NeurologiquesSame topicGout, Hyperuricemia, Uric AcidFrench-language works237,207