CO<sub>2</sub>-Switchable Supramolecular Block Glycopolypeptide Assemblies
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
A novel supramolecular block glycopolypeptide, designed to have the viral building blocks and be sensitive to CO 2, a physiological stimulus, was prepared via the orthogonal coupling of two end-functionalized biopolymers, dextran with β-cyclodextrin terminal (Dex-CD) and poly( l -valine) with a benzimidazole tail (BzI-PVal), respectively, driven by the end-to-end host–guest interactions. Due to the CO 2 -cleavable CD/BzI connection, both the vesicular and fibrous aggregates of this supramolecular block copolymer self-assembled in aqueous solution can undergo a reversible process of disassembly upon “breathing in” CO 2 and assembly upon “breathing out” CO 2, which mimics, to some extent, the disintegration and construction of viral capsid nanostructures.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.004 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it