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A Moderate Dose of Pseudoephedrine Does Not Alter Muscle Contraction Strength or Anaerobic Power

2002· article· en· W2332004779 on OpenAlexaff
Kelly S. Chu, Timothy J. Doherty, Gianni Parise, Jaime Milheiro, Mark A. Tarnopolsky

Bibliographic record

VenueClinical Journal of Sport Medicine · 2002
Typearticle
Languageen
FieldMedicine
TopicPharmacology and Obesity Treatment
Canadian institutionsMcMaster UniversityMcMaster University Medical Centre
Fundersnot available
KeywordsMedicineAnaerobic exercisePlaceboPseudoephedrineCrossover studyAnkleWingate testMuscle fatigueIngestionAnesthesiaPhysical therapyInternal medicineEphedrinePhysical medicine and rehabilitationSurgeryElectromyography

Abstract

fetched live from OpenAlex

OBJECTIVE: To investigate the effect of an acute oral administration of pseudoephedrine (PSE) on muscle function, fatigue, and anaerobic power output. DESIGN AND MATERIALS: Healthy males (N = 10) and females (N = 10) were allocated to receive both a placebo and PSE (120 mg) using a randomized, double-blind, crossover experimental design. Each subject had their maximal voluntary contraction strength and fatigability measured for both handgrip and ankle dorsi-flexion. Following the strength measurements, a 30-second maximal cycle test was performed to determine lower extremity anaerobic power and fatigue. Plasma lactate was measured before and after exercise. RESULTS: There were no significant differences in any of the outcome variables between the placebo and PSE trials. CONCLUSIONS: These results demonstrated that a 120 mg dose of PSE did not enhance force production, time to fatigue, fatigue index, or power output in young men or women. Therefore, there does not appear to be an ergogenic benefit from the ingestion of 120 mg PSE in high-intensity exercise performance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.269
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.391
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2002
Admission routes1
Has abstractyes

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