Automation and remote control of the MX beamlines at the Canadian Light Source
Bibliographic record
Abstract
Poster Sessions C276 proteins are 0.097 GPa -1 and 0.076 GPa -1 , respectively.It may imply that SoIPMDH, which is from land bacteria, is more sensitive to pressure than SbIPMDH from extremophile.The SoIPMDH structure shows a dimer that presents an internal hydrophobic cavity surrounded by Pro120，Lue121，Ile125， Lue232 and Lue258 at the dimer interface.Two structurally functional water molecules appeared in the cavity at a pressure of 470 MPa, while no such water molecule could be observed under atmospheric pressure.Previous published works assume that the pressure denaturation of proteins is induced by water penetration into the hydrophobic interior of proteins.Although concrete data are lacking, several theoretical and simulation studies support this theory [2].The present observation is a direct evidence of the fact that water molecules do penetrate into the inner cavities of proteins under high pressure.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.003 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.064 | 0.013 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".