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Record W2332172300 · doi:10.3934/mbe.2014.11.1139

On optimization of substrate removal in a bioreactor with wall attached and suspended bacteria

2014· article· en· W2332172300 on OpenAlexaff
Alma Mašić, Hermann J. Eberl

Bibliographic record

VenueMathematical Biosciences & Engineering · 2014
Typearticle
Languageen
FieldEngineering
Topic3D Printing in Biomedical Research
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsBioreactorBacteriaSubstrate (aquarium)ChemistryBiochemical engineeringChemical engineeringMicrobiologyBiologyEcologyEngineeringOrganic chemistry

Abstract

fetched live from OpenAlex

We investigate the question of optimal substrate removal in a biofilm reactor with concurrent suspended growth, both with respect to the amount of substrate removed and with respect to treatment process duration. The water to be treated is fed externally from a buffer vessel to the treatment reactor. In the two-objective optimal control problem, the flow rate between the vessels is selected as the control variable. The treatment reactor is modelled by a system of three ordinary differential equations in which a two-point boundary value problem is embedded. The solution of the associated singular optimal control problem in the class of measurable functions is impractical to determine and infeasible to implement in real reactors. Instead, we solve the simpler problem to optimize reactor performance in the class of off-on functions, a choice that is motivated by the underlying biological process. These control functions start with an initial no-flow period and then switch to a constant flow rate until the buffer vessel is empty. We approximate the Pareto Front numerically and study the behaviour of the system and its dependence on reactor and initial data. Overall, the modest potential of control strategies to improve reactor performance is found to be primarily due to an initial transient period in which the bacteria have to adapt to the environmental conditions in the reactor, i.e. depends heavily on the initial state of the dynamic system. In applications, the initial state, however, is often unknown and therefore the efficiency of reactor optimization, compared to the uncontrolled system with constant flow rate, is limited.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.445
Threshold uncertainty score0.397

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.230
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2014
Admission routes1
Has abstractyes

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