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Record W2332416201 · doi:10.1021/jp303932k

Multi-edge X-ray Absorption Spectroscopy. 1. X-ray Absorption near-Edge Structure Analysis of a Biomimetic Model of FeFe-Hydrogenase

2012· article· en· W2332416201 on OpenAlexfundno aff
Logan J. Giles, Alexios Grigoropoulos, Róbert K. Szilágyi

Bibliographic record

VenueThe Journal of Physical Chemistry A · 2012
Typearticle
Languageen
FieldEnergy
TopicMetalloenzymes and iron-sulfur proteins
Canadian institutionsnot available
FundersCanadian Institutes of Health Research
KeywordsChemistryXANESX-ray absorption spectroscopyAtomic orbitalCovalent bondMolecular orbitalCrystallographyK-edgeAbsorption spectroscopyAtom (system on chip)Bond lengthElectronSpectroscopyMoleculePhysicsCrystal structure

Abstract

fetched live from OpenAlex

In this work, we demonstrate the potential of multi-edge X-ray absorption near-edge structure (XANES) analysis in completely defining the ground state electronic structure of a prototypical biomimetic complex of the [2Fe]-subcluster of the catalytic H-cluster of FeFe-hydrogenase. The spectral features at the ionization thresholds for Fe, S, C, and O 1s (K-edge) and Fe 2p (L-edge) core electrons were considered simultaneously to obtain the atomic compositions of the unoccupied frontier molecular orbitals. A systematic error analysis was carried out at the most informative S K-edge for spectra collected by multiple detection methods, at various data collection temperatures, and different sample preparation protocols. As expected for the difference in bonding between bridging and terminal Fe-S(thiolate) coordination, the Fe-S bond is more covalent in the [2Fe]-biomimetic complex with formally iron(I) centers (36 ± 2% S character per Fe-S bond) than in the previously described [2Fe-2S] clusters (25 ± 3% S character per Fe-S bond) with formally iron(III) centers. An electron hole-based analysis of the pre-edge features at Fe K-, Fe L-, and S K-edges experimentally defines the composition of the first three frontier unoccupied molecular orbitals to contain 4% Fe 4p, 44% Fe 3d, and 24% S 3p contributions per electron hole, respectively. The complementary CO ligand contribution thus can be defined as 28% per electron hole. These experimental orbital covalency values are important in rationalizing redox properties, electrophilicity of the metals, or nucleophilicity of the ligands, and critically evaluating the absolute accuracy of electronic structure calculations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.258
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2012
Admission routes1
Has abstractyes

Explore more

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