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Record W2333733246 · doi:10.1177/1715163516640811

Prescribing cascade in an elderly woman

2016· article· en· W2333733246 on OpenAlexaffvenue
Patrick Viet-Quoc Nguyen, Caroline Spinelli

Bibliographic record

VenueCanadian Pharmacists Journal / Revue des Pharmaciens du Canada · 2016
Typearticle
Languageen
FieldMedicine
TopicPharmaceutical Practices and Patient Outcomes
Canadian institutionsCentre Hospitalier de l’Université de Montréal
Fundersnot available
KeywordsPolypharmacyMedicineMedical prescriptionLimitingDrug reactionIntensive care medicineDrugPediatricsPsychiatryPharmacology

Abstract

fetched live from OpenAlex

Background Prescribing cascades usually occur when signs and symptoms of a patient are inaccurately assessed and an adverse drug reaction (ADR) is misinterpreted as a new condition, resulting in a new medication being prescribed. The prevalence of prescribing cascades is currently unknown. Prescribing cascades often lead to polypharmacy, especially in elderly people. In the United States, one study reported that 57% of women aged 65 years and older take 5 prescription drugs or more and 12% take more than 9. Polypharmacy is also a risk factor for ADRs, which cause 12% of all hospital admissions. Limiting prescribing cascades could therefore help to prevent ADRs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.462
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.123
GPT teacher head0.356
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations32
Published2016
Admission routes2
Has abstractyes

Explore more

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