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Record W2334848003 · doi:10.1016/j.juro.2016.02.390

PD28-03 COMPLIANCE WITH EVIDENCE BASED BONE HEALTH MANAGEMENT IN MEN ON CHRONIC ADT: OPPORTUNITIES FOR IMPROVEMENT

2016· article· en· W2334848003 on OpenAlexaboutno aff
Franklin Gaylis, Jaclyn B. Gaylis, Kevin C. McGill, Sothary Julie Van, Hilary Prime, Jenna Essakow, Renee Calabrese, Susan S. Levy, Paul Dato

Bibliographic record

VenueThe Journal of Urology · 2016
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSexual Differentiation and Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineAndrogen deprivation therapyVitamin D and neurologyOsteoporosisGerontologyFamily medicineCancerInternal medicineProstate cancer

Abstract

fetched live from OpenAlex

You have accessJournal of UrologyProstate Cancer: Advanced (including Drug Therapy) I1 Apr 2016PD28-03 COMPLIANCE WITH EVIDENCE BASED BONE HEALTH MANAGEMENT IN MEN ON CHRONIC ADT: OPPORTUNITIES FOR IMPROVEMENT Franklin Gaylis, Jaclyn Gaylis, Kevin McGill, Sothary Julie Van, Hilary Prime, Jenna Essakow, Renee Calabrese, Susan S. Levy, and Paul Dato Franklin GaylisFranklin Gaylis More articles by this author , Jaclyn GaylisJaclyn Gaylis More articles by this author , Kevin McGillKevin McGill More articles by this author , Sothary Julie VanSothary Julie Van More articles by this author , Hilary PrimeHilary Prime More articles by this author , Jenna EssakowJenna Essakow More articles by this author , Renee CalabreseRenee Calabrese More articles by this author , Susan S. LevySusan S. Levy More articles by this author , and Paul DatoPaul Dato More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.390AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Men on chronic Androgen Depravation Therapy (ADT) are at risk for bone demineralization and complications including fracture. The National Osteoporosis Foundation recommendations include a baseline assessment of bone density with a DEXA scan and daily calcium and Vitamin D supplementation. In this study we report compliance with these evidence based guidelines. METHODS Cohort included 500 men treated with chronic ADT (defined as > 1 year). EMR (Allcripts TM) was queried for baseline Calcium, Vitamin D and DEXA scanning at the onset of ADT. The EMR was automatically queried by the WIzMDTM software program electronically abstracting both structured and unstructured data. Trained data analysts manually abstracted the same data for comparison and validation. Bone health management compliance was compared between a dedicated Advanced Prostate Cancer Center (APCC) and the Primary Urology Office (PUO). RESULTS Calcium and/or Vitamin D was prescribed to 33% of the 500 patient cohort. Of these patients, 25% were prescribed both Vitamin D and Calcium. 5%, and 3% were prescribed either Vitamin D or Calcium, respectively. 12.8% of all patients received a baseline DEXA scan. A dedicated centralized Advanced Prostate Cancer Center (APCC) was compared to the Primary Urology Office (PUO) for compliance with baseline DEXA scanning and Calcium/Vitamin D prescription. Chi-square tests of independence revealed a significant relationship (p < .001) between health management delivery site and receipt of a baseline DEXA scan for those who qualified, with 78% at the APCC receiving a scan compared to 22% at the PUO. Similarly, significant relationships (p < .001) were found between delivery care site and compliance to recommended vitamin D and Calcium supplementation. Of those receiving care at the APCC, 76.6 % complied to recommendations and 23.4% did not, compared to PUO care-delivered patients, of whom 24.9% complied to recommendations and 75.1% did not. Inter-abstractor reliability was preformed by randomly reviewing 10% of the data, yielding a 90% agreement between data abstractors. CONCLUSIONS Men at risk for adverse bone consequences from chronic ADT do not always receive care according to evidence based guidelines. These findings call for improved processes that standardize evidence based practice including baseline and follow up bone density assessment and daily calcium and vitamin D supplementation. Our findings of significantly improved compliance at a dedicated Advanced Prostate Cancer Center, highlights the value of dedicated physicians and nurses in a centralized facility, managing patients with advanced prostate cancer. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e655 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Franklin Gaylis More articles by this author Jaclyn Gaylis More articles by this author Kevin McGill More articles by this author Sothary Julie Van More articles by this author Hilary Prime More articles by this author Jenna Essakow More articles by this author Renee Calabrese More articles by this author Susan S. Levy More articles by this author Paul Dato More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.541
Threshold uncertainty score0.166

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.317
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2016
Admission routes1
Has abstractyes

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