Interactive Effects Between Extraversion and Oxytocin Administration
Bibliographic record
Abstract
Intranasal administration of the neuropeptide oxytocin (OT) appears to have positive social consequences, but these effects are often highly context- and person-specific. The present research examined whether the core personality trait of extraversion may be one important person-specific factor that plays a role in these associations. Across two double-blind randomized placebo-controlled studies (total ns: Study 1 = 121; Study 2 = 112), we observed significant interactions between OT administration and extraversion predicting prosocial outcomes. For individuals low in extraversion, OT administration relative to placebo led to greater perceived social connection and prosocial tendencies (Study 1) and more positive behavioral responses to help and greater trust of an interaction partner (Study 2). In contrast, OT administration was not beneficial for individuals high in extraversion. Overall, these findings contribute to growing evidence that OT administration has complex, person-specific effects on social behavior, indicating that extraversion plays an important role in these associations.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".