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Record W2336336020 · doi:10.1039/9781849733519-00371

Glycoproteins and Adhesion Ligands: Properties and Biomedical Applications

2011· book-chapter· en· W2336336020 on OpenAlexaff
Brenda K. Mann, Suzanne D. Turner

Bibliographic record

Venuenot available
Typebook-chapter
Languageen
FieldMedicine
TopicCell Adhesion Molecules Research
Canadian institutionsCanada Research ChairsUniversity of Toronto
Fundersnot available
KeywordsFibronectinGlycoproteinBiomaterialExtracellular matrixLamininAdhesionCell adhesionChemistryTissue engineeringCell biologyCellBiochemistryBiologyEngineeringBiomedical engineering

Abstract

fetched live from OpenAlex

Glycoproteins are a class of multifunctional proteins in the extracellular matrix (ECM) of tissues that serve to link cells to the ECM, link proteins to one another, and mediate cell behavior. Structural glycoproteins, in particular, have found uses in biomaterial and tissue engineering applications. This chapter outlines two representative glycoproteins, fibronectin and laminin, adhesion peptide sequences derived from them, and their use in biomaterial applications. In general, the proteins and peptides have been adsorbed or covalently attached to biomaterial surfaces, as well as incorporated in tissue engineering scaffolds. These modifications promote cell attachment and may help to direct specific desired cell responses.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.017
Threshold uncertainty score0.058

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0170.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.269
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2011
Admission routes1
Has abstractyes

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