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Record W2337851457 · doi:10.17576/mjas-2016-2001-01

Antibacterial and Antioxidant Activity of Lichens Usnea rubrotincta, Ramalina dumeticola, Cladonia verticillata and Their Chemical Constituents

2016· article· en· W2337851457 on OpenAlex
Saranyapiriya Gunasekaran, Vinoshene Pillai, Surash Ramanathan, Vikneswaran Murugaiyah, Mohd Wahid Samsudin, Laily B. Din

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueMalaysian Journal of Analytical Science · 2016
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicLichen and fungal ecology
Canadian institutionsCentre for Drug Research and Development
FundersUniversiti Sains MalaysiaUniversiti Kebangsaan MalaysiaMinistry of Higher Education, Malaysia
KeywordsLichenAntioxidantChemistryBotanyBiologyOrganic chemistry

Abstract

fetched live from OpenAlex

The present study was carried out to evaluate the antibacterial and antioxidant activity of extract and chemical constituents of Usnea rubrotincta, Ramalina dumeticola and Cladonia verticillata. Acetone extract of U. rubrotincta showed promising antibacterial activity against Gram positive bacteria Bacillus subtilis with the lowest Minimal Inhibitory Concentration (MIC) value of (15.63 g/mL). Six secondary metabolites were isolated using Preparative High Performance Liquid Chromatography (PHPLC) method from the two bioactive lichens U. rubrotincta and R. dumeticola (compound 1 -6). Among all six compounds, compound (1) exhibited strongest activity against both the tested Gram positive bacteria at 7.81 g/mL. Compound (6) had 69.57% scavenging activity against DPPH free radical while the rest only showed below 50% scavenging activity. This is the first evaluation of antibacterial activity of lichens found in Malaysia and to our knowledge, this is the first report of antibacterial and antioxidant activity of compound (3) and (5).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.833
Threshold uncertainty score0.661

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.219
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it