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Record W2339186904 · doi:10.7448/ias.19.1.20707

A picture is worth a thousand words: maps of HIV indicators to inform research, programs, and policy from NA‐ACCORD and CCASAnet clinical cohorts

2016· article· en· W2339186904 on OpenAlexafffundabout
Keri N. Althoff, Peter F. Rebeiro, David Hanna, Denis Padgett, Michael A. Horberg, Beatriz Grinsztejn, Alison G. Abraham, Robert S. Hogg, M. John Gill, Marcelo Wolff, Ángel M. Mayor, Anita Rachlis, Carolyn Williams, Timothy R. Sterling, Mari M. Kitahata, Kate Buchacz, Jennifer E. Thorne, Carina César, Fernando Mejía Cordero, Sean B. Rourke, Juan Sierra‐Madero, Jean W. Pape, Pedro Cahn, Catherine C. McGowan

Bibliographic record

VenueJournal of the International AIDS Society · 2016
Typearticle
Languageen
FieldMedicine
TopicData-Driven Disease Surveillance
Canadian institutionsHealth Sciences CentreUniversity of TorontoSunnybrook Health Science CentreUniversity of CalgaryAIDS Vancouver
FundersNational Institute of Allergy and Infectious DiseasesNational Eye InstituteNational Institute on Drug AbuseU.S. Public Health ServiceNational Institute on Minority Health and Health DisparitiesNational Center for Research ResourcesCenters for Disease Control and PreventionNational Cancer InstituteNational Institute on Alcohol Abuse and AlcoholismKaiser PermanenteCase Western Reserve UniversityUniversidad de ChileEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentUniversity of North Carolina at Chapel HillAgency for Healthcare Research and QualityGovernment of AlbertaJohns Hopkins UniversityCanadian Institutes of Health ResearchUniversity of WashingtonNational Institutes of HealthVanderbilt UniversityNational Center for Advancing Translational SciencesHealth Resources and Services Administration
KeywordsMedicineHuman immunodeficiency virus (HIV)Antiretroviral therapyDemographyCohortEpidemiologyHealth careViral loadGeographyGerontologyFamily medicineEconomic growthPathology

Abstract

fetched live from OpenAlex

INTRODUCTION: Maps are powerful tools for visualization of differences in health indicators by geographical region, but multi-country maps of HIV indicators do not exist, perhaps due to lack of consistent data across countries. Our objective was to create maps of four HIV indicators in North, Central, and South American countries. METHODS: Using data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) and the Caribbean, Central, and South America network for HIV epidemiology (CCASAnet), we mapped median CD4 at presentation for HIV clinical care, proportion retained in HIV primary care, proportion prescribed antiretroviral therapy (ART), and the proportion with suppressed plasma HIV viral load (VL) from 2010 to 2012 for North, Central, and South America. The 15 Canadian and US clinical cohorts and 7 clinical cohorts in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, and Peru represented approximately 2-7% of persons known to be living with HIV in these countries. RESULTS: Study populations were selected for each indicator: median CD4 at presentation for care was estimated among 14,811 adults; retention was estimated among 87,979 adults; ART use was estimated among 84,757 adults; and suppressed VL was estimated among 51,118 adults. Only three US states and the District of Columbia had a median CD4 at presentation >350 cells/mm(3). Haiti, Mexico, and several states had >85% retention in care; lower (50-74%) retention in care was observed in the US West, South, and Mid-Atlantic, and in Argentina, Brazil, and Peru. ART use was highest (90%) in Mexico. The percentages of patients with suppressed VL in the US South and Northeast were lower than in most of Central and South America. CONCLUSIONS: These maps provide visualization of gaps in the quality of HIV care and allow for comparison between and within countries as well as monitoring policy and programme goals within geographical boundaries.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.097
Threshold uncertainty score0.255

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.383
Teacher spread0.345 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2016
Admission routes3
Has abstractyes

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