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Record W2343981703 · doi:10.1155/2016/5743521

Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan

2016· article· en· W2343981703 on OpenAlexafffundabout
Selena M. Sagan, Benoît Dupont, Jason Grebely, Mel Krajden, Sonya A. MacParland, Jennifer F. Raven, Sahar Saeed, Jordan J. Feld, D. Lorne Tyrrell, Joyce A. Wilson

Bibliographic record

VenueCanadian Journal of Gastroenterology and Hepatology · 2016
Typearticle
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsToronto Western HospitalInstitute of Infection and ImmunityCanadian Institutes of Health ResearchUniversity of British ColumbiaBC Centre for Disease ControlUniversity of SaskatchewanUniversity of AlbertaUniversité de MontréalUniversity Health NetworkMcGill University
FundersCanadian Institutes of Health ResearchAlberta InnovatesNational Health and Medical Research CouncilDalhousie UniversityUniversity of AlbertaUniversity of New South WalesMedical Research CouncilCanadian Liver FoundationUniversité de MontréalArdakan UniversityAustralian GovernmentGilead SciencesSimon Fraser UniversityUniversity of OttawaMcGill UniversityBristol-Myers SquibbUniversity of TorontoEmory University
KeywordsAction planMedicineHepatitis CDiseaseAgency (philosophy)Public healthHepatitis C virusDisease burdenDisease EradicationFamily medicineIntensive care medicineImmunologyVirusNursingPathologyManagement

Abstract

fetched live from OpenAlex

Hepatitis C virus (HCV) affects at least 268,000 Canadians and causes greater disease burden than any other infectious disease in the country. The Canadian Institutes of Health Research (CIHR) and the Public Health Agency of Canada (PHAC) have identified HCV-related liver disease as a priority. In 2015, the release of well-tolerated, short course treatments (~12 weeks) able to cure the majority of treated HCV patients revolutionized HCV therapy. However, treatment is extremely costly and puts a significant burden on the Canadian healthcare system. Thus, managing treatment costs and improving treatment engagement in those most in need will be a key challenge. Diagnosis and treatment uptake are currently poor in Canada due to financial, geographical, cultural, and social barriers. The United States, Australia, and Scotland all have National Action Plans to prevent, diagnose, and treat HCV in order to efficiently reduce the burden and costs associated with HCV-related liver disease. The theme of the 4th annual symposium held on Feb 27, 2015, "Strategies to Manage HCV Infection in Canada: Moving towards a National Action Plan," was aimed at identifying strategies to maximize the impact of highly effective therapies to reduce HCV disease burden and ultimately eliminate HCV in Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.955
Threshold uncertainty score0.938

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.014
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.001
Science and technology studies0.0080.003
Scholarly communication0.0080.003
Open science0.0040.005
Research integrity0.0130.018
Insufficient payload (model declined to judge)0.0270.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.274
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2016
Admission routes3
Has abstractyes

Explore more

Same venueCanadian Journal of Gastroenterology and HepatologySame topicHepatitis C virus researchFrench-language works237,207