Early influnce on blood-testis barrier induced by electromagnetic pulse and expression of TGFβ3 in mouse testis
Bibliographic record
Abstract
Objective To study the early influnce of blood-testis barrier induced by electromagnetic pulse irradiation in mouse and the mechanism of action of TGFβ3 expression in this process.Methods Routine HE staining and lanthanum tracing electron microscopy were used to observe the influence of 400 kV/m electromagnetic pulse irradiation on mouse blood-testis barrie within 2~48 h.Immunohistochemical method and image analysis were used to analyze the possible role of TGFβ3 in this process.Results After 400 kV/m electromagnetic pulse irradiation,spermatogenic cells presented degeneration,apoptosis and necrosis,the shape and structure of Sertoli's cell and tight junction were changed,blood-testis barrier was injuried seriously and its permeability increased within 48 h.TGF-β3 mainly expressed in the cytoplasm of Leydig's cells and interstitial tissue,and its expression persistently increased within 2~48 h(P0.05).Conclusion The structural and functional damages of mouse blood-testis barrier rapidly occurred after electromagnetic pulse irradiation,and TGFβ3 may play an important role in this damaging process.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".