Relationship between plasma homocysteine and mild cognitive impairment in patients with cerebral small vessel disease
Bibliographic record
Abstract
Objective To explore the relationship between plasma homocysteine(Hcy)and vascular mild cognitive impairment(VMCI)in patients with cerebral small vessel disease(SVD).Methods Plasma Hcy,folic acid and VitB12were determined in 82cases of VMCI patients with cerebral SVD(VMCI group)and 60healthy subjects(control group),who were scored with Montreal Cognitive Assessment(MoCA).Correlation between plasma Hcy level and MoCA scores was analyzed.Results Plasma Hcy level in VMCI group was significantly higher than that in control group(P0.01),but plasma levels of folic acid and VitB12,MoCA total score and MoCA subscore with regard to composition of the cube,clock drawing test,recognition of target digit and delayed recall were lower than control group(P0.01).Plasma Hcy level was negatively correlated with plasma level of folic acid and VitB12and MoCA total score in VMCI group(P0.05).Conclusion Increased plasma level of Hcy could be closely related to cognitive impairment in patients with cerebral SVD,and cognitive of abstract space configuration and attention might be decreased earlier in patients with VMCI.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".