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Record W2348158049

Multicenter Randomized Controlled Clinical Trial On Teicoplanin Versus Vancomycin

2002· article· en· W2348158049 on OpenAlexaff
Fang Lv

Bibliographic record

VenueThe Chinese Journal of Clinical Pharmacology · 2002
Typearticle
Languageen
FieldMedicine
TopicAntimicrobial Resistance in Staphylococcus
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsTeicoplaninMedicineVancomycinAdverse effectRandomized controlled trialGram-positive bacterial infectionsInternal medicineAnesthesiaGastroenterologySurgeryAntibioticsStaphylococcus aureusMicrobiologyBacteriaBiology
DOInot available

Abstract

fetched live from OpenAlex

OBJECTIVE: To Evaluate the efficacy and safety of teicoplanin. METHODS: The patients received teicoplanin intravenously once daily at 400mg in the first day, 200mg from the second day and the doses were double for the patients with severe infections, or vancomycin at 0.5g three times daily and 1.0g twice daily for the patients with severe infections. The treatment duration was 7-14 days. RESULTS: The effective rate and cure rate were 87.10% (54/62) and 74.19%(46/62)in teicoplanin group, while in vancomycin group were 90.32%(56/62)and 61.29%(38/62) respectively. The bacterial elimination rate was 94.74%(54/57) in teicoplanin group and 88.52%(54/61) in vancomycin group. Adverse reactions occurred in 11.29%(7/62) of patients in teicoplanin group and 6.45%(4/62) in vancomycin group. There were no statistically differences between the two groups. CONCLUSION: Teicoplanin is an effective and safe agent for treating moderate and severe gram positive bacterial infections.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.028
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.067
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0130.028
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.004
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.099
GPT teacher head0.481
Teacher spread0.382 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2002
Admission routes1
Has abstractyes

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