Estudio comparativo de la determinación del metronidazol en formulaciones farmacéuticas, mediante voltametría de pulso diferencial y espectroscopia de Infrarrojo con transformada de fourier
Bibliographic record
Abstract
In this work, a comparative study for the determination of the antibiotic metronidazole was performed in two different pharmaceutical formulations by Fourier transformed infrared spectroscopy and differential pulse voltammetry. The differential pulse voltammetry shows a reduction response of the antibiotic on glassy carbon electrode at 0.55 V vs. Ag/AgNO3 at san rate of 5 mVs-1 in a Britton-Robinson Buffer at pH 4.5. Detection limit of 7.17 x 10-7 M was achieved, and a recovery average 101.4% and 97.4% for the tablet and intravenous solution respectively. For the Fourier transformed infrared spectroscopy technique, pure acetonitrile was used as solvent, and the band of the C-O Group at 1188 cm-1 was employed for the quantification. Detection limit of 8.9 x 10-6 M with an average recovery of 117,7% for the Tablets and 101.0% for the intravenous solution.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".