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Record W2348629818 · doi:10.1016/j.gheart.2014.03.2169

PW005 Safety and efficacy of dabigatran compared to warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation

2014· article· en· W2348629818 on OpenAlexaff
Nitin Kansal, Natalia Pinilla, Sam Schulman, Carlos A. Morillo

Bibliographic record

VenueGlobal Heart · 2014
Typearticle
Languageen
FieldMedicine
TopicHER2/EGFR in Cancer Research
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedicineRheumatoid arthritisTransforming growth factorAngiogenesisApoptosisArthritisDabigatranCancer researchAtrial fibrillationImmunologyInternal medicineWarfarinBiology

Abstract

fetched live from OpenAlex

TGF-β is a cytokine with pleiotropic functions in hematopoiesis, angiogenesis, cell proliferation, differentiation, migration and apoptosis. Although its role in rheumatoid arthritis is not well defined, TGF-β activation leads to functional immunomodulatory effects according to environmental conditions. The function of TGF-β in the development of arthritis in murine models has been extensively studied with controversial results. Recent findings point to a non-relevant role for TGF-β in a mice model of collagen-induced arthritis. The study of TGF-β on T-cell responses has shown controversial results as an inhibitor or promoter of the inflammatory response. This paper presents a review of the role of TGF-β in animal models of arthritis.El TGF-β es una citocina implicada en procesos celulares como hematopoyesis, proliferación, angiogénesis, diferenciación, migración y apoptosis celular. Aunque su papel en la artritis reumatoide no está bien definido, está considerada como una citocina inmunomoduladora según las condiciones del entorno. Numerosos trabajos han tratado de definir el papel del TGF-β en el desarrollo de la artritis murina en diferentes modelos de enfermedad, con resultados discordantes. De hecho, resultados recientemente publicados indican que TGF-β no desempeña un papel relevante en el modelo murino de artritis inducida con colágeno. Su implicación en la diferenciación y la funcionalidad de las diferentes poblaciones de células T también ha mostrado resultados dispares sobre su papel como inhibidor o promotor de la respuesta inflamatoria. En este trabajo se presenta una revisión sobre el papel de TGF-β en modelos animales de artritis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.047
Threshold uncertainty score0.422

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.362
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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