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Record W2356789662

Study on the antitumor effect of extracts from scale and shell of Crocodylus porosus

2006· article· en· W2356789662 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueZhongguo haiyang yaowu · 2006
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicMedicinal Plant Pharmacodynamics Research
Canadian institutionsL'Alliance Boviteq
Fundersnot available
KeywordsCrocodylusPharmacologyBiologyChemistryEcology
DOInot available

Abstract

fetched live from OpenAlex

Objective To study the inhibitory effects of the Crocodylus porosus extracts on murine tumor. Methods 3% of papain was used to degrade the scale and shell of the Crocodylus porosus for 14 hours under 60℃,pH7.0. The effects of the extracts on hepatic solid tumor (HepA) and Ehrlich ascites carcinoma (EAC) were studied in mice. Results The inhibitory rates of the high-dose extract (4.5g·kg~ -1 ) on HepA and EAC were 30.01%(P0.05)and 37.69%(P0.05)respectively,and the inhibitory rates of the low-dose extract (2.25g·kg~ -1 )were 21.43%(P0.05)and 37.69%(P0.01)respectively. The high-dose extracts(4.5g·kg~ -1 ) could prolong 21.12%(P0.05)and 34.39%(P0.05)of the life span of HepA bearing mice and EAC bearing mice, and the low-dose (2.25g·kg~ -1 )were 39.13%(P0.01)and 1.91%(P0.05)respectively. Conclusion It is indicated by the primary research that the Crocodylus porosus extracts have inhibitory effects on the murine tumor.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.089
Threshold uncertainty score0.740

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.076
GPT teacher head0.434
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it