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Record W2356789662

Study on the antitumor effect of extracts from scale and shell of Crocodylus porosus

2006· article· en· W2356789662 on OpenAlexaff
Xueting Mei, XU Dong-hui, Jiang Ci-lian, Haiping Ma, Shibo Xu

Bibliographic record

VenueZhongguo haiyang yaowu · 2006
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicMedicinal Plant Pharmacodynamics Research
Canadian institutionsL'Alliance Boviteq
Fundersnot available
KeywordsCrocodylusPharmacologyBiologyChemistryEcology
DOInot available

Abstract

fetched live from OpenAlex

Objective To study the inhibitory effects of the Crocodylus porosus extracts on murine tumor. Methods 3% of papain was used to degrade the scale and shell of the Crocodylus porosus for 14 hours under 60℃,pH7.0. The effects of the extracts on hepatic solid tumor (HepA) and Ehrlich ascites carcinoma (EAC) were studied in mice. Results The inhibitory rates of the high-dose extract (4.5g·kg~ -1 ) on HepA and EAC were 30.01%(P0.05)and 37.69%(P0.05)respectively,and the inhibitory rates of the low-dose extract (2.25g·kg~ -1 )were 21.43%(P0.05)and 37.69%(P0.01)respectively. The high-dose extracts(4.5g·kg~ -1 ) could prolong 21.12%(P0.05)and 34.39%(P0.05)of the life span of HepA bearing mice and EAC bearing mice, and the low-dose (2.25g·kg~ -1 )were 39.13%(P0.01)and 1.91%(P0.05)respectively. Conclusion It is indicated by the primary research that the Crocodylus porosus extracts have inhibitory effects on the murine tumor.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.076
GPT teacher head0.434
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes1
Has abstractyes

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