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Record W2357492210

Clinic study on uric acid in patients with Parkinson′s disease

2011· article· en· W2357492210 on OpenAlexaboutno aff
Zhan Xiao

Bibliographic record

VenueLaboratory Medicine and Clinic · 2011
Typearticle
Languageen
FieldSocial Sciences
TopicPsychosocial Factors Impacting Youth
Canadian institutionsnot available
Fundersnot available
KeywordsUric acidParkinson's diseaseInternal medicineMedicineGastroenterologyDepression (economics)DiseaseMoodRating scaleEndocrinologyPsychologyPsychiatry
DOInot available

Abstract

fetched live from OpenAlex

Objective To explore the relation between uric acid in patients with Parkinson′s disease(PD) and motor symptoms and non-motor symptoms.Methods 101 patients with PD were classified as PD,male PD and female PD groups and their serum uric acid contents were examined,and 100 healthy persons whose age,sex matched the patients were enrolled as the controls.We used unified Parkinson diseases rating scale part Ⅲ,the PD NMS Questionnaire and Montreal Cognitive Assessment and Hamilton Depression Rating Scale to assess the patients.Results The serum uric acid level in PD(315.4±71.83 μmol/L) was lower than that in the controls [(332.06±83.36)μmol/L,P0.05].The serum uric acid level in PD was gender related and male PD patients(336.01±74.72) μmol/L had a higher serum uric acid level than female patients[(293.25±108.84)μmol/L,P0.05].In male PD patients,the serum uric acid level was correlated with clinical types(r=0.342,P0.05).In PD patients(r=-0.255,P0.05)and female PD patients(r=-0.32,P0.05),the serum uric acid level was correlated with mood and recognition symptoms in NMS Quest.Conclusion Lower serum uric acid level is probable a risk facor in PD.There are some correlations between serum uric acid level and motor symptoms and non-motor symptoms,which needs further investigation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.372
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2011
Admission routes1
Has abstractyes

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