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Record W2360222879

Preparation and controlled release properties of cell outer membrane mimetic structures of chitosan nanoparticles

2014· article· en· W2360222879 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Functional Biomaterials · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA Interference and Gene Delivery
Canadian institutionsScience North
Fundersnot available
KeywordsMaterials scienceDynamic light scatteringNanoparticleZeta potentialChitosanDrug deliveryPotassium persulfateMembraneChemical engineeringPolymerizationMethacrylic acidTransmission electron microscopyMonomerNanotechnologyPolymerChemistryComposite materialBiochemistry
DOInot available

Abstract

fetched live from OpenAlex

The cell outer membrane mimetic structures of nanoparticles were prepared using methacrylic acid( MA),2-methacryloyloxyethyl phosphorylcholine( MPC) as monomer,potassium persulfate( KPS) and chitosan by template polymerization. The size distribution and structure properties of nanoparticles were characterized by transmission electron microscopy( TEM),dynamic light scattering( DLS) and zeta potential. The drug release properties of nanoparticles were estimated by doxorubicin in vitro release experiment. The cell outer membrane mimetic structures of nanoparticles might have potential applications in the fields of gene therapy and drug delivery. The controlled release properties had been an important academic significance on the study of outer cell membrane structures of nanoparticles.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.221

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.224
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it