Preparation and control release properties of chitosan electrostatic assembly with polyanion bearing phosphorylcholine groups
Bibliographic record
Abstract
Novel polyelectrolyte hydrogels were prepared by polycation chitosan(CS)and polyanionic poly(2-methacryloyloxyethyl phosphorylcholine-co-methacrylic acid)(poly(MPC-co-MA),PMA30).The PMA30(the actual percentages of MPC unit in PMA30 determined by 1 H-NMR was 28%)was synthesized by free radical polymerization of 2-methacryloyloxyethyl phosphorylcholine(MPC)and methacrylic acid(MA).Fourier transform infrared spectra(FT-IR)and scanning electron microscopy(SEM)confirmed that the formation of the polyelectrolyte hydrogels was attributed to the strong electrostatic interaction between cationic groups in CS and anionic groups in PMA30.Potential applications of the hydrogels matrices in controlled drug delivery were also examined.In vitro release showed that neutral red release could be controlled by choosing the composition and pH.This facile method of fabricating CS/PMA30 hydrogels bearing phosphorylcholine groups may have potential applications in the fields of drug delivery,tissue engineering,and cell culture.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".