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Record W2367027523 · doi:10.2310/6650.2005.x0004.373

374 NUTRITIONAL FAILURE AND CACHEXIA IN A PEDIATRIC PALLIATIVE CARE POPULATION.

2006· article· en· W2367027523 on OpenAlex
Harold Siden, Gordon S. Soon, Kelly Cox, Lynn Straatman

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Investigative Medicine · 2006
Typearticle
Languageen
FieldNursing
TopicClinical Nutrition and Gastroenterology
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineMalnutritionBloatingPalliative careIntensive care medicineParenteral nutritionIleusAbdominal painPediatricsPopulationCachexiaArtificial nutritionSurgeryInternal medicineCancerEnvironmental health

Abstract

fetched live from OpenAlex

<h3></h3> Children with neurologic and metabolic conditions face significant challenges with nutrition. Often, they require assistance with feeding, whether surgical or medical, to prevent weight loss and malnutrition. Among pediatric palliative caregivers, the phenomenon of nutritional failure is known to occur in these children at the end of life; however, it has never been documented in the literature. The goal of this research study was to retrospectively illustrate and document the time course of nutritional failure in children with metabolic and/or neurologic conditions by reviewing a select series of cases. Our hypothesis was that unexplained nutritional failure is a marker for the end of life trajectory in children with these underlying diseases. An extensive review of literature regarding the above phenomenon was performed. In addition, a series of representative cases from children who died while at Canuck Place—a pediatric palliative hospice—was studied. Charts were reviewed for information regarding the nutrition route and composition, the results of relevant laboratory and imaging studies, and the symptoms of feeding intolerance that led to nutritional failure prior to death. Nutritional failure, which manifested as progressive intolerance of enteral feeding despite modifications in the artificial route used, the formula composition, and the use of a variety of medications, was observed in the representative cases of children. Symptoms of worsening gastroesophageal reflux, vomiting, abdominal bloating, ileus, seizures, and pain preceded the end of life in each of the case studies. The clinical phenomenon of nutritional failure at end of life is an important guide to the management of these children as well as a prognostic indicator for both clinicians and families.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.126
Threshold uncertainty score0.404

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.312
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it