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Record W2370543969

Efficacy of diacerein,glucosamine sulfate and sodium hyaluronate on knee osteoarthritis

2013· article· en· W2370543969 on OpenAlexaboutno aff
Huang Jin-xia

Bibliographic record

VenueShiyong yixue zazhi · 2013
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
Fundersnot available
KeywordsSodium hyaluronateOsteoarthritisGlucosamineMedicineWOMACVisual analogue scaleSurgeryChemistry
DOInot available

Abstract

fetched live from OpenAlex

Objective To investigate the efficacy of diacerein,glucosamine sulfate and sodium hyaluronate on knee osteoarthritis(KOA). Methods 80 patients with KOA were randomly divided into 2 groups. 40 cases in observation group received oral diacerein and glucosamine sulfate for 12 weeks,and received intra-articular injection of sodium hyaluronate once a week for 5 weeks. 40 cases in control group only received oral glucosamine sulfate and intra-articular injection of sodium hyaluronate with the same dosage and course. Visual analog scale(VAS) assessment on pain of walking for 20 meters,tenderness on palpation and Western Ontario and McMaster Universities OA(WOMAC) index were evaluated before and after the treatment. Results The assessment indices were significantly improved in both groups after the treatment(P 0.05),and the improvement was more significant in observation group than that in control group(P 0.05). During the treating process,no severe adverse events were observed in both groups. Conclusions Diacerein,glucosamine sulfate in combination with sodium hyaluronate treatment had prominent effect,was tolerable and safe,and worth clinical promotion.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.884
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.229
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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