Efficacy of diacerein,glucosamine sulfate and sodium hyaluronate on knee osteoarthritis
Bibliographic record
Abstract
Objective To investigate the efficacy of diacerein,glucosamine sulfate and sodium hyaluronate on knee osteoarthritis(KOA). Methods 80 patients with KOA were randomly divided into 2 groups. 40 cases in observation group received oral diacerein and glucosamine sulfate for 12 weeks,and received intra-articular injection of sodium hyaluronate once a week for 5 weeks. 40 cases in control group only received oral glucosamine sulfate and intra-articular injection of sodium hyaluronate with the same dosage and course. Visual analog scale(VAS) assessment on pain of walking for 20 meters,tenderness on palpation and Western Ontario and McMaster Universities OA(WOMAC) index were evaluated before and after the treatment. Results The assessment indices were significantly improved in both groups after the treatment(P 0.05),and the improvement was more significant in observation group than that in control group(P 0.05). During the treating process,no severe adverse events were observed in both groups. Conclusions Diacerein,glucosamine sulfate in combination with sodium hyaluronate treatment had prominent effect,was tolerable and safe,and worth clinical promotion.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".