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Record W2371624953

Impact of microwave radiation on the structure of sinoatrial node in the rat heart

2012· article· en· W2371624953 on OpenAlexaff
Yanqing Liu

Bibliographic record

VenueChinese Journal of Stereology and Image Analysis · 2012
Typearticle
Languageen
FieldImmunology and Microbiology
TopicBiomarkers in Disease Mechanisms
Canadian institutionsCAE (Canada)
Fundersnot available
KeywordsSinoatrial nodeMicrowave irradiationIrradiationChemistryMicrowavePathologyNuclear magnetic resonanceInternal medicineBiophysicsMedicineBiologyHeart rateBiochemistryPhysicsBlood pressure
DOInot available

Abstract

fetched live from OpenAlex

Objective To observe the structural changes in the sinoatrial node of rat heart after microwave irradiation and its dose-effect relationship.Methods One hundred and twenty Wistar rats were exposed to microwave field at different average power densities: 0,5,10,50 mW/cm 2,for 6 min.The rats were killed on d1,d7,d14,d28,m3 and m6 after microwave irradiation.Sinoatrial nodes were taken to make paraffin sections for histological examination.The structural changes of the sinoatrial nodes and the content of collagen fibers were observed by light microscopy after HE and Masson staining and assessed by image analysis.Results(1) There were no significant changes in the sinoatrial nodes in the 5 mW/cm 2 group.Edema of P and T cells in the sinoatrial nodes in the 10 mW/cm 2 and 50 mW/cm 2 groups were observed on d1 after microwave irradiation and gradually worsened.Disorganization of sinoatrial node cells,cytoplasmic condensation and even karyopyknosis in some cells were observed on d14 in the those two groups.Gradual recovery occurred from d28 to m6 in the 10 mW/cm 2 and 50 mW/cm 2 groups.At 6 m after microwave irradiation,the injury did not return to normal level yet.(2) The content of collagen fibers in the sinoatrial nodes of the 50 mW/cm 2 group was significantly increased on m3(P 0.05) and m6(P 0.01) after microwave irradiation.The above described changes showed a dose-effect relationship.Conclusions Microwave irradiation at an average power density from 10 mW/cm 2 to 50 mW/cm 2 can cause structural injuries in the rat sinoatrial nodes with a dose-effect relationship.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.546
Threshold uncertainty score0.341

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.268
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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